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Biocrush^®

(Herbal formula for Gynaecological tumors)

Scientific background

Cancer is the second most common health problem in women world-wide especially cervical cancer with more than 470,000 new cases per year. Of about 230,000 deaths every year, more than 80% occur in developing countries.
Sexually transmitted infection with human papilloma virus is fundamental to development of carcinoma of the cervix.
Population-based screening has greatly reduced mortality in developing countries.
Endometrial cancer mainly affects postmenopausal women in developed countries : 188,000 new cases are diagnosed annually and obesity is a major risk factor.
About 190,000 cases of ovarian cancer occur each year, predominantly among postmenopausal women in developed countries.

Composition

Each caplet contains:
Vitis spp. rhizome extract ....... 250 mg
(Vitis discolor and Vitis repens)

Plant description

Vitis discolor and Vitis repens are widely distributed in Shan State. Vitis species are tendrillar climbers, slender, scandent, glabrous. Glaucous with fusiform to tuberculous rhizome. The tendrils borne at the nodes, opposed to the leaf, forked at the tips. Stems 6-angled with ridges and furrows. Leaves alternate, simple, the tips acuminate, margin serrulate, base truncate to cordate. Inflorescence axillary, compound umbellate cymes, flowers small yellowish green, bracteate. Fruits berries, globose, darkred, shining black in fully ripe. Vitis discolor and Vitis repens are identified, according to the leaves and flowers character. The leaf of Vitis discolor is green above, variegated with white and purple beneath, lanceolate from cordate base. The flower of Vitis discolor is red inconspicuous. The leaf of Vitis repens is pale green on both surface, the upper surface blotched with white, ovate from cordate base. The flower of Vitis repens is red conspicuous.

Pharmacological actions

In Myanmar, one of the effective antitumor herbal medicinal plants is Vitis species (Tabin- daing-mya-nan). Vitis species (Vitis discolor and Vitis repens) isolate glycosides, flavonoids, 3 keto steroids, bergenin, vitisonol B, vitisonol C, vitisonol D, vitisin A, vitisin B, isolariciresinol, 4-O-methyl gallate, protocatechuic, gallic acid, pallidol, onocer-7-en-3a, 21b -diol (I) and onecer 7-en-3a , 21a-diol (II) as bioactive compounds. Vitis discolor and Vitis repens rhizome have the most active compounds in Vitis species on phytochemical tests. According to in vitro and in vivo studies, these compounds have inhibitory effects on dividing tumor cells of the female genital tract such as tumors of cervix, uterus and ovaries.

Indication

Dosage

One to two caplets two times daily, depending on site, type and severity of tumor.

Contraindication

• Pregnancy
• Lactating mother
• Children under 2 year
• Patient with anticoagulant therapy

Combination therapy

Biocrush® shoud be used in combination with Completec® and Fame Chlorella® to obtain maximum therapeutic benefit.

Side effects

Caution

Keep out of the reach of children.

How supply

30 caplets per bottle.